abstract：:The aim of this study was to evaluate the relationship of prognosis of patients with multiple myeloma having extramedullary involvement (EMM) with the 18F- fluorodeoxyglucose(18F-FDG) maximum standardized uptake value and the expression of Ki-67 in biopsy samples. Sixty-five patients were newly diagnosed with multiple...

journal_title：Technology in cancer research & treatment

authors： Li Q,Ma J,Li H,Xu W,Cao Z,Liu S,Chen L,Gao S,Yan T,Li D,Wang X,Yue Y,Zhao Z,Wang X,Yang H,Zhao H,Yu Y,Zhang Y,Fan F,Wang Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Nonthermal irreversible electroporation is a minimally invasive surgery technology that employs high and brief electric fields to ablate undesirable tissues. Nonthermal irreversible electroporation can ablate only cells while preserving intact functional properties of the extracellular structures. Therefore,...

journal_title：Technology in cancer research & treatment

authors： Lv Y,Zhang Y,Huang J,Wang Y,Rubinsky B

更新日期：2019-01-01 00:00:00

abstract：:Tumor-infiltrating immune cells are part of a complex microenvironment and associated with improved clinical outcomes in a broad range of tumor types. However, a detailed map for the prognostic landscape of tumor-infiltrating immune cells and immune checkpoint modulators in glioblastoma is still lacking. Here, with th...

journal_title：Technology in cancer research & treatment

authors： Wu S,Yang W,Zhang H,Ren Y,Fang Z,Yuan C,Yao Z

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Our objective is to explore the accuracy of magnetic resonance imaging in determining the preoperative T and N staging, pathological stage, and the length of esophageal tumor in patients with esophageal cancer. METHODS:This retrospective analysis included 57 patients admitted to the Department of Thoracic S...

journal_title：Technology in cancer research & treatment

authors： Gao Z,Hua B,Ge X,Liu J,Xue L,Zhen F,Luo J

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:We investigated the dosimetric effect of intrafraction tumor motion in lung stereotactic body radiotherapy using the CyberKnife static tracking system. METHODS:Four-dimensional computed tomography scans of a dynamic thorax phantom were acquired. Two motion ranges, 3 collimator sizes, and 4 treatment starting p...

journal_title：Technology in cancer research & treatment

authors： Chang Y,Liu HY,Liang ZW,Nie X,Yang J,Liu G,Li Q,Yang ZY

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the prognostic role of neutrophil to lymphocyte ratio in ovarian cancer. Growing number of articles reported the relationship between neutrophil to lymphocyte ratio and prognosis in ovarian cancer, but the results remains inconclusive. The meta-analysis was conducted to...

journal_title：Technology in cancer research & treatment

authors： Chen G,Zhu L,Yang Y,Long Y,Li X,Wang Y

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The main objective in studying large-scale cancer omics is to identify molecular mechanisms of cancer and discover novel biomedical targets. This work not only discovers the cancer subtypes in genome scale data by using clustering and classification but also measures their accuracy. METHODS:Initially, candid...

journal_title：Technology in cancer research & treatment

authors： Vasudevan P,Murugesan T

更新日期：2018-01-01 00:00:00

abstract：:Poorly differentiated cell populations including tumor-initiating stem cells have been demonstrated to display a unique ability to natively internalize fragmented double-stranded DNA. Using this feature as a marker, we show that 0.1% to 6% of human glioblastoma cells from the bioptates can effectively internalize a fl...

journal_title：Technology in cancer research & treatment

authors： Dolgova EV,Mishinov SV,Proskurina AS,Potter EA,Efremov YR,Bayborodin SI,Tyrinova TV,Stupak VV,Ostatin AA,Chernykh ER,Bogachev SS

更新日期：2018-01-01 00:00:00

abstract：:Targeted immunotherapy using dendritic cell vaccine has been employed for the treatment of solid tumors. Topical 5-aminolevulinic acid-mediated photodynamic therapy, an established approach for topical cancers, can induce an effective antitumor immune response. We have previously shown that 5-aminolevulinic acid-media...

journal_title：Technology in cancer research & treatment

authors： Zhang H,Wang P,Wang X,Shi L,Fan Z,Zhang G,Yang D,Bahavar CF,Zhou F,Chen WR,Wang X

更新日期：2018-01-01 00:00:00

abstract：:Since "Warburg effect" has been firstly uncovered in cancer cells in 1956, mounting evidence has supported the molecular mechanism underlying the energy metabolism in induced chemoresistance in cancers. MicroRNAs can mediate fine-tuning of genes in physiological process. MicroRNAs' energy metabolic role in chemoresist...

journal_title：Technology in cancer research & treatment

authors： Ye J,Zou M,Li P,Liu H

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:In this study, we aimed to evaluate the prognostic value of fluorodeoxyglucose uptake in the lung parenchyma and the presence of subclinical interstitial lung disease on computed tomography as predictive factors for survival following stereotactic body radiation therapy in patients with stage I non-small cell l...

journal_title：Technology in cancer research & treatment

authors： Satoh Y,Motosugi U,Saito A,Omiya Y,Onishi H

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the mechanisms involved with miRNA-708 and its targeting of bone morphogenetic protein and activin membrane-bound inhibitor in cell proliferation, migration, and apoptosis in mice with melanoma via the Wnt and transforming growth factor β signaling pathways. METHODS:Sixt...

journal_title：Technology in cancer research & treatment

authors： Lu HJ,Yan J,Jin PY,Zheng GH,Zhang HL,Bai M,Wu DM,Lu J,Zheng YL

更新日期：2018-01-01 00:00:00

abstract：:Routine follow-up visits and radiographic imaging are required for outcome evaluation and tumor recurrence monitoring. Yet more personalized surveillance is required in order to sufficiently address the nature of heterogeneity in nonsmall cell lung cancer and possible recurrences upon completion of treatment. Radiomic...

journal_title：Technology in cancer research & treatment

authors： Shi L,He Y,Yuan Z,Benedict S,Valicenti R,Qiu J,Rong Y

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:There is mounting evidence that microRNAs play an important role in nasopharyngeal carcinoma, which is widely prevalent in South China and is the most prevalent metastatic cancer among head and neck cancers. Recently, it has been shown that miR-494 is involved in the progression and prognosis of nasopharynge...

journal_title：Technology in cancer research & treatment

authors： He H,Liao X,Yang Q,Liu Y,Peng Y,Zhong H,Yang J,Zhang H,Yu Z,Zuo Y,Guan C,Xu Z

更新日期：2018-01-01 00:00:00

abstract：:Hepatocellular carcinoma is the fourth leading cause of cancer-related death worldwide. Depending on the extent of disease and competing comorbidities for mortality, multiple liver-directed therapy options exist for the treatment of hepatocellular carcinoma. Advancements in radiation oncology have led to the emergence...

journal_title：Technology in cancer research & treatment

authors： Schaub SK,Hartvigson PE,Lock MI,Høyer M,Brunner TB,Cardenes HR,Dawson LA,Kim EY,Mayr NA,Lo SS,Apisarnthanarax S

更新日期：2018-01-01 00:00:00

abstract：:The ultrasound-guided diffuse optical tomography is a noninvasive imaging technique for breast cancer diagnosis and treatment monitoring. The technique uses a handheld probe capable of providing measurements of multiple wavelengths in a few seconds. These measurements are used to estimate optical absorptions of lesion...

journal_title：Technology in cancer research & treatment

authors： Althobaiti M,Vavadi H,Zhu Q

更新日期：2018-01-01 00:00:00

abstract：:Most experimental studies of electroporation focus on permeabilization of the outer cell membrane. Some experiments address delivery of ions and molecules into cells that should survive; others focus on efficient killing of the cells with minimal temperature rise. A basic method for quantifying electroporation effecti...

journal_title：Technology in cancer research & treatment

authors： Sweeney DC,Weaver JC,Davalos RV

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIM:Methylated SEPT9 is a novel circulating tumor DNA marker for colorectal cancer, while the effects of various colorectal cancer clinicopathological factors on its detection performance have not been fully evaluated. This study aims to investigate the significance of the clinicopathological factors on ...

journal_title：Technology in cancer research & treatment

authors： He N,Song L,Kang Q,Jin P,Cai G,Zhou J,Zhou G,Sheng J,Cai S,Wang J,Han X,Nie Y,Wu K

更新日期：2018-01-01 00:00:00

abstract：:Lung cancer remains one of the most common cancer-related deaths worldwide. The cigarette smoking is a risk factor for lung cancer development. Interestingly, the cystic fibrosis transmembrane conductance regulator encoded by CFTR gene, an ATP-binding cassette transporter-class ion channel that conducts chloride and b...

journal_title：Technology in cancer research & treatment

authors： Li H,Ma N,Wang J,Wang Y,Yuan C,Wu J,Luo M,Yang J,Chen J,Shi J,Liu X

更新日期：2018-01-01 00:00:00

abstract：:Mesenchymal stromal cells are proven to be likely induce the angiogenic response in multiple myeloma and thus represent an enticing target for antiangiogenesis therapies for multiple myeloma. Substantial evidence indicates that angiogenesis in multiple myeloma is complex and involves direct production of angiogenic cy...

journal_title：Technology in cancer research & treatment

authors： Zhang X,Xu Y,Liu H,Zhao P,Chen Y,Yue Z,Zhang Z,Wang X

更新日期：2018-01-01 00:00:00

abstract：:We used a shifted-excitation Raman difference spectroscopy method for the ex vivo classification of resected and formalin-fixed breast tissue samples as normal (healthy) tissue, fibroadenoma, or invasive carcinoma. We analyzed 8 tissue samples containing invasive carcinoma that were surrounded by normal tissue and 3 t...

journal_title：Technology in cancer research & treatment

authors： Gebrekidan MT,Erber R,Hartmann A,Fasching PA,Emons J,Beckmann MW,Braeuer A

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:The aim of the in vivo dosimetry, during the fractionated radiation therapy, is the verification of the correct dose delivery to patient. Nowadays, in vivo dosimetry procedures for photon beams are based on the use of the electronic portal imaging device and dedicated software to elaborate electronic portal ima...

journal_title：Technology in cancer research & treatment

authors： Falco MD,Giancaterino S,De Nicola A,Adorante N,De Lorenzo RG,Di Tommaso M,Vinciguerra A,Trignani M,Perrotti F,Allajbej A,Fidanzio A,Greco F,Grusio M,Genovesi D,Piermattei A

更新日期：2018-01-01 00:00:00

abstract：:Stereotactic body radiation therapy is a well-tolerated modality for the treatment of primary and metastatic liver lesions, and fiducials are often used as surrogates for tumor tracking during treatment. We evaluated respiratory-induced liver deformation by measuring the rigidity of the fiducial configuration during t...

journal_title：Technology in cancer research & treatment

authors： Paulsson AK,Yom SS,Anwar M,Pinnaduwage D,Sudhyadhom A,Gottschalk AR,Chang AJ,Descovich M

更新日期：2017-12-01 00:00:00

abstract：:Histological differentiation is a major pathological criterion indicating the risk of tumor invasion and metastasis in patients with hepatocellular carcinoma. The degree of tumor differentiation is controlled by a complex interacting network of associated proteins. The principal aim of the present study is to identify...

journal_title：Technology in cancer research & treatment

authors： Zhao S,Su G,Yang W,Yue P,Bai B,Lin Y,Zhang J,Ba Y,Luo Z,Liu X,Zhao L,Xie Y,Xu Y,Li S,Meng W,Xie X,Li X

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:We recently developed a novel, open-source in vivo dosimetry that uses the electronic portal imaging device to detect dose delivery discrepancies. We applied our method on patients with rectal cancer treated on a belly board device. METHODS:In vivo dosimetry was performed on 10 patients with rectal cancer trea...

journal_title：Technology in cancer research & treatment

authors： Peca S,Sinha RS,Brown DW,Smith WL

更新日期：2017-12-01 00:00:00

abstract：:One of the most lethal carcinomas is pancreatic cancer. As standard treatment using chemotherapy and radiation has shown limited success, thermal regimens (cryotherapy or heat ablation) are emerging as viable alternatives. Although promising, our understanding of pancreatic cancer response to thermal ablation remains ...

journal_title：Technology in cancer research & treatment

authors： Baumann KW,Baust JM,Snyder KK,Baust JG,Van Buskirk RG

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:The study was aimed to compare online 6 degree-of-freedom image registrations of TrueBeam cone-beam computed tomography and BrainLab ExacTrac X-ray imaging systems for intracranial radiosurgery. METHODS:Phantom and patient studies were performed on a Varian TrueBeam STx linear accelerator (version 2.5), which ...

journal_title：Technology in cancer research & treatment

authors： Li J,Shi W,Andrews D,Werner-Wasik M,Lu B,Yu Y,Dicker A,Liu H

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To assess the efficacy of stereotactic body radiotherapy in patients with unresectable locally advanced pancreatic cancer. MATERIALS AND METHODS:All patients received a prescription dose of 45 Gy in 6 fractions. Primary end point was freedom from local progression. Secondary end points were overall survival, p...

journal_title：Technology in cancer research & treatment

authors： Comito T,Cozzi L,Clerici E,Franzese C,Tozzi A,Iftode C,Navarria P,D'Agostino G,Rimassa L,Carnaghi C,Personeni N,Tronconi MC,De Rose F,Franceschini D,Ascolese AM,Fogliata A,Tomatis S,Santoro A,Zerbi A,Scorsetti M

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:The efficacy of image-guided high-dose rate brachytherapy for cervical cancer is limited by the ineffective rectal sparing devices available commercially and the potential applicator movement. We developed a novel device using a balloon catheter and a belt immobilization system, serving for rectal dose reductio...

journal_title：Technology in cancer research & treatment

authors： Fan Q,Yeung AR,Amdur R,Helmig R,Park J,Li J,Kahler D,Liu C,Lu B

更新日期：2017-06-01 00:00:00

abstract：:The purpose of this research is to establish a process of irradiating mice using the Gamma Knife as a versatile system for small animal irradiation and to validate accurate intracranial and extracranial dose delivery using this system. A stereotactic immobilization device was developed for small animals for the Gamma ...

journal_title：Technology in cancer research & treatment

authors： Awan MJ,Dorth J,Mani A,Kim H,Zheng Y,Mislmani M,Welford S,Yuan J,Wessels BW,Lo SS,Letterio J,Machtay M,Sloan A,Sohn JW

更新日期：2017-04-01 00:00:00

abstract：:At external beam radiotherapy, stereoscopic X-ray imaging system is responsible as tumor motion information provider. This system takes X-ray images intermittently from tumor position (1) at pretreatment step to provide training data set for model construction and (2) during treatment to control the accuracy of correl...

journal_title：Technology in cancer research & treatment

authors： Esmaili Torshabi A,Ghorbanzadeh L

更新日期：2017-04-01 00:00:00

abstract：:A specific protein profile that accompanies neoplastic transformation in the premalignant airway epithelium could provide an opportunity for early diagnosis of lung cancer. The aim of this study was to screen and identify early candidate biomarkers of non-small cell lung cancer. Thirteen non-small cell lung cancer sam...

journal_title：Technology in cancer research & treatment

authors： Nan Y,Du J,Ma L,Jiang H,Jin F,Yang S

更新日期：2017-02-01 00:00:00

abstract：:We have developed a small animal conformal radiation therapy device that provides a degree of geometrical/anatomical targeting comparable to what is achievable in a commercial animal irradiator. small animal conformal radiation therapy device is capable of producing precise and accurate conformal delivery of radiation...

journal_title：Technology in cancer research & treatment

authors： Sharma S,Narayanasamy G,Przybyla B,Webber J,Boerma M,Clarkson R,Moros EG,Corry PM,Griffin RJ

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. MATERIALS AND METHODS:A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identi...

journal_title：Technology in cancer research & treatment

authors： Korpics M,Johnson P,Patel R,Surucu M,Choi M,Emami B,Roeske JC

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:To test the feasibility of modified biopsy needles as probes for irreversible electroporation ablation and periprocedural biopsy. METHODS:Core biopsy needles of 16-G/9-cm were customized to serve as experimental ablation probes. Computed tomography-guided percutaneous irreversible electroporation was perfor...

journal_title：Technology in cancer research & treatment

authors： Wimmer T,Srimathveeravalli G,Silk M,Monette S,Gutta N,Maybody M,Erinjery JP,Coleman JA,Solomon SB,Sofocleous CT

更新日期：2016-12-01 00:00:00

abstract：:Glypican-3 has been reported to be one of the most promising serum markers for hepatocellular carcinoma. This study aimed to assess the clinical utility of serum glypican 3 for the diagnosis of hepatocellular carcinoma. We recruited consecutive patients on a large scale, 283 with hepatocellular carcinoma, 445 with chr...

journal_title：Technology in cancer research & treatment

authors： Jia X,Gao Y,Zhai D,Liu J,Cai J,Wang Y,Jing L,Du Z

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Antibody resistance, both de novo and acquired, is usually related to high risk of recurrence and lower survival rate in gynecologic cancers. Prevention or reversal of the resistance often yields beneficial clinical results. It was reported that anti-human epidermal growth factor receptor 3 monoclonal antibo...

journal_title：Technology in cancer research & treatment

authors： Li X,Duan Y,Qiao C,Zhou T,Yu M,Geng J,Feng J,Shen B,Lv M,Li Y

更新日期：2016-08-01 00:00:00

abstract：:This study aims to reduce the uncertainty about the photoneutron dose produced over a course of radiotherapy with high-energy photon beams and evaluate photoneutron contamination-based secondary malignancy risk for different treatment modalities. Dosimetric measurements were taken in Philips SL25/75, Elekta Synergy Pl...

journal_title：Technology in cancer research & treatment

authors： Biltekin F,Yeginer M,Ozyigit G

更新日期：2016-08-01 00:00:00

abstract：:Tumstatin (Tum) is a powerful angiostatin that inhibits proliferation and induces apoptosis of tumorous vascular endothelial cells. A nonpathogenic and anaerobic bacterium, Bifidobacterium longum (BL), selectively localizes to and proliferates in the hypoxia location within solid tumor. The aims of this study were to ...

journal_title：Technology in cancer research & treatment

authors： Wei C,Xun AY,Wei XX,Yao J,Wang JY,Shi RY,Yang GH,Li YX,Xu ZL,Lai MG,Zhang R,Wang LS,Zeng WS

更新日期：2016-06-01 00:00:00

abstract：:This study was performed to observe the effect of the combination of nimotuzumab with radiation or gemcitabine-based chemoradiation on antipancreatic cancer cell therapy. Pancreatic cancer cells (PANC-1) were treated with nimotuzumab alone or combined with radiation (2, 4, or 8 Gy), which was either with or without ge...

journal_title：Technology in cancer research & treatment

authors： Gao C,Wu X,Yan Y,Meng L,Shan D,Li Y,Han B

更新日期：2016-06-01 00:00:00